4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone

• Catalog No.: M325751
• CAS Number: 764661-24-7
• M. F.: C10H13N3O2
• M. W.: 207.22912
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-[methyl(nitroso)amino]-1-[(^2H₄)pyridin-3-yl]butan-1-one
• IUPAC Traditional name: 4-[methyl(nitroso)amino]-1-[(^2H₄)pyridin-3-yl]butan-1-one
• Synonyms: NNK-d4; 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl-d4)-1-butanone

DATABASE IDS

• CAS Number: 764661-24-7

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 58-60°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled NNK (M325750). This compound was present in the highest concentrations in smokeless tobacco out of the nitrosamines identified. It is likely to be important in the etiology of cancers of the lung, oral cavity, and pancreas in people who use taba

REFERENCES

• Koenigs, L., et al.: Drug Metab. Dispos., 25, 1407 (1997)
• Gu, J., et al.: Toxicol. Appl. Pharmacol., 165, 158 (1997)
• Jalas, J., et al.: Chem. Res. Toxicol., 18, 95 (1997)
• Zhu, L., et al.: Drug Metab. Dispos., 34, 1672 (1997)