4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

• Catalog No.: M325750
• CAS Number: 64091-91-4
• M. F.: C10H13N3O2
• M. W.: 207.22912
• Storage: Amber Vial, -20°C Freezer

SYNONYMS

• IUPAC name: 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one
• IUPAC Traditional name: nnk (carcinogen)
• Synonyms: 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; NNK

DATABASE IDS

• CAS Number: 64091-91-4

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 65-67°C
• Solubility: Dichloromethane
• Solubility: DMF
• Solubility: DMSO
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: Amber Vial, -20°C Freezer

DETAILS

Description (English)

This compound was present in the highest concentrations in smokeless tobacco out of the nitrosamines identified. It is likely to be important in the etiology of cancers of the lung, oral cavity, and pancreas in people who use tabacco products. Readily pr

REFERENCES

• Koenigs, L., et al.: Drug Metab. Dispos., 25, 1407 (1997)
• Gu, J., et al.: Toxicol. Appl. Pharmacol., 165, 158 (1997)
• Jalas, J., et al.: Chem. Res. Toxicol., 18, 95(1997)
• Zhu, L., et al.: Drug Metab. Dispos., 34, 1672(1997)