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N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonamide_Molecular_structure_CAS_108409-83-2)
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N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonamide

Catalog No. M325350 Name Toronto Research Chemicals
CAS Number 108409-83-2 Website http://www.trc-canada.com
M. F. C13H10Cl2N2O4S Telephone +1 (416) 665-9696
M. W. 361.2005 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 153682

SYNONYMS

IUPAC name
2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzene-1-sulfonamide
IUPAC Traditional name
2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide
Synonyms
2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide

DATABASE IDS

CAS Number 108409-83-2

PROPERTIES

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DETAILS

Description (English)
Antagonizes Wnt/β-catenin/Tcf-mediated transcription as well as PPARγ and δ activity. Able to inhibit the recruitment of the co-activators β-catenin and GRIP1, both of which are activators for both pathways.

REFERENCES

  • Handeli, S., et al.: Mol. Cancer Ther., 7, 521 (2008)