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β-Methyl Digoxin

Catalog No. M301850 Name Toronto Research Chemicals
CAS Number 30685-43-9 Website http://www.trc-canada.com
M. F. C42H66O14 Telephone +1 (416) 665-9696
M. W. 794.96504 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, Refrigerator, Under Inert Atmosphere Chembase ID: 173557

SYNONYMS

IUPAC name
4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-5-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]-2,5-dihydrofuran-2-one
IUPAC Traditional name
metildigoxin
Synonyms
Medigoxin
Metildigoxin
Lanitop
(3β,5β,12β)-3-[(O-2,6-Dideoxy-4-O-methyl-β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
4'''-Methyldigoxin
4'''-O-Methyldigoxin
Lanirapid
Methyldigoxin

DATABASE IDS

CAS Number 30685-43-9

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 200-202°C (dec.)
Solubility DMSO
MSDS Link Download
Storage Condition Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)
Cardiotonic. Obtained by the O-methylation of Digoxin.

REFERENCES

  • Hunter, J., et al.: J. Biol. Chem., 268, 14991 (1993)
  • Greiner, B., et al.: J. Clin. Invest., 104, 147 (1993)
  • Jun, A., et al.: J. Pharm.Pharm. Sci., 4, 263 (1993)
  • Sugiyama, D., et al.: Drug Metab. Dispos., 30, 220 (1993)