β-Methyl Digoxin

• Catalog No.: M301850
• CAS Number: 30685-43-9
• M. F.: C42H66O14
• M. W.: 794.96504
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-5-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]-2,5-dihydrofuran-2-one
• IUPAC Traditional name: metildigoxin
• Synonyms: Medigoxin; Metildigoxin; Lanitop; (3β,5β,12β)-3-[(O-2,6-Dideoxy-4-O-methyl-β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; 4'''-Methyldigoxin; 4'''-O-Methyldigoxin; Lanirapid; Methyldigoxin

DATABASE IDS

• CAS Number: 30685-43-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 200-202°C (dec.)
• Solubility: DMSO
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Cardiotonic. Obtained by the O-methylation of Digoxin.

REFERENCES

• Hunter, J., et al.: J. Biol. Chem., 268, 14991 (1993)
• Greiner, B., et al.: J. Clin. Invest., 104, 147 (1993)
• Jun, A., et al.: J. Pharm.Pharm. Sci., 4, 263 (1993)
• Sugiyama, D., et al.: Drug Metab. Dispos., 30, 220 (1993)