2'-O-Methyl Adenosine

• Catalog No.: M276150
• CAS Number: 2140-79-6
• M. F.: C11H15N5O4
• M. W.: 281.2679
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
• IUPAC Traditional name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
• Synonyms: 5-(6-Aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol; 2'-O-Methyl-D-adenosine

DATABASE IDS

• CAS Number: 2140-79-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 198-200°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Adenosine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

REFERENCES

• Eldrup, A.B., et al.: J. Med. Chem., 47, 2283 (2004)
• Shim, J., et al.: Antiviral Res., 243 (2004)
• Wang, M., et al.: J. Biol. Chem., 278, 9489 (2004)