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α-Methyl Omuralide

Catalog No. M265145 Name Toronto Research Chemicals
CAS Number 215232-00-1 Website http://www.trc-canada.com
M. F. C11H17NO4 Telephone +1 (416) 665-9696
M. W. 227.25698 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 173078

SYNONYMS

IUPAC name
(1R,5S)-1-[(1S)-1-hydroxy-2-methylpropyl]-4,4-dimethyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione
IUPAC Traditional name
(1R,5S)-1-[(1S)-1-hydroxy-2-methylpropyl]-4,4-dimethyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione
Synonyms
(-)-7-Methylomuralide
(1R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4,4-dimethyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

DATABASE IDS

CAS Number 215232-00-1

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Potent, selective, irreversible inhibitor of proteasome function. A cell permeable α-methyl analog of clasto-Lactacytin (C562500).

REFERENCES

  • Saravanan, P. et al.: J. Org. Chem. 68, 2760 (2003)
  • Corey, E.J., et al.: Tetrahedron Lett. 39, 7475 (2003)