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2-Methoxy 17β-Estradiol_Molecular_structure_CAS_362-07-2)
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2-Methoxy 17β-Estradiol

Catalog No. M262625 Name Toronto Research Chemicals
CAS Number 362-07-2 Website http://www.trc-canada.com
M. F. C19H26O3 Telephone +1 (416) 665-9696
M. W. 302.40794 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 72585

SYNONYMS

IUPAC name
(1S,10R,11S,14S,15S)-4-methoxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2(7),3,5-triene-5,14-diol
IUPAC Traditional name
2-methoxyestradiol
Synonyms
2-Methoxyestra-1,3,5(10)-triene-3,17β-diol
NSC 659853
Panzem
(17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol
2-Hydroxyestradiol 2-methyl ether
2-Methoxyestradiol

DATABASE IDS

CAS Number 362-07-2

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 188-190°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
2-Methoxy 17β-Estradiol is a natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. 2-Methoxy 17β-Estradiol binds to the colchicine binding site of tubulin, and has been suggested to func

REFERENCES

  • Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995)
  • D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1995)
  • Forsis, T., et al.: Nature, 368, 237 (1994)