β-Methadol-d3 Hydrochloride

• Catalog No.: M225912
• M. F.: C21H30ClNO
• M. W.: 347.922

SYNONYMS

• IUPAC name: (3S,6R)-6-(dimethylamino)-4,4-diphenyl(1,1,1-^2H₃)heptan-3-ol hydrochloride
• IUPAC Traditional name: (3S,6R)-6-(dimethylamino)-4,4-diphenyl(1,1,1-^2H₃)heptan-3-ol hydrochloride
• Synonyms: β-6-Dimethylamino-4,4-diphenyl-3-heptanol-d3 Hydrochloride; (αS)-β-[(2R)-2-(Dimethylamino)propyl]-α-ethyl-β-phenylbenzeneethanol-d3 Hydrochloride; (-)-β-Methadol-d3 Hydrochloride; [S-(R*,S*)]-β-[2-(Dimethylamino)propyl]-α-ethyl-β-phenylbenzeneethanol-d3 Hydrochloride; (3S,6R)-Methadol-d3 Hydrochloride; Betamethadol-d3 Hydrochloride; (3S,6R)-(-)-6-(Dimethylamino)-4,4-diphenyl-3-heptanol-d3 Hydrochloride

DETAILS

Description (English)

A labelled analgesic derivative of the synthetic μ-opiate agonist (R)-Methadone (M225880) and a precursor of β-Acetylmethadol. It does not evoke heroin-like discriminative stimulus effects unlike other methadone derivatives. It has inhibitory effect on 5-

REFERENCES

• Newman, J.L. et al.: Psychopharmacol., 164, 108 (2002)
• Brase, D.A. et al.: Biochem. Pharmacol., 25, 1684 (2002)
• Casy, A.F. et al.: J. Med. Chem., 11, 601 (2002)