S-(+)-Mecamylamine Hydrochloride

• Catalog No.: M202595
• CAS Number: 107596-30-5
• M. F.: C11H22ClN
• M. W.: 203.75208
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1R,2S,4S)-N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride
• IUPAC Traditional name: (1R,2S,4S)-N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride
• Synonyms: (1R,2S,4S)-N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine Hydrochloride; (1R-exo)-N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine Hydrochloride; (+)-Mecamylamine Hydrochloride; NIH 11008; TC 5214

DATABASE IDS

• CAS Number: 107596-30-5

PROPERTIES

• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Apperance: White Solid
• Melting Point: 255-260°C
• Solubility: Chloroform
• Solubility: Methanol

DETAILS

Description (English)

The S-(+) enantiomer of Mecamylamine (M202600), a noncompetitive neuronal nicotinic receptor modulator antagonist with antidepressant activity.

REFERENCES

• Fryer, J., et al.: J. Pharmacol. Exp. Ther., 288, 88 (1999)
• Slemmer, J., et al.: J. Pharmacol. Exp. Ther., 295, 321 (1999)
• Young, J., et al.: Clin. Ther., 23, 532 (1999)