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MDV 3100-d3
Catalog No.	M199802	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C21H16F4N4O2S	Telephone	+1 (416) 665-9696
M. W.	464.4359528	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 172562

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SYNONYMS

IUPAC name

4-{3-[3-cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-2-fluoro-N-(²H₃)methylbenzamide

IUPAC Traditional name

4-{3-[3-cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-2-fluoro-N-(²H₃)methylbenzamide

Synonyms

4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)benzamide

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)

Labelled MDV 3100. MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to ind

REFERENCES

Scher, H.I. et al.: Lancet, 375, 1437 (2010)
Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010)
Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2010)