Lubiprostone-d7

• Catalog No.: L473503
• M. F.: C20H32F2O5
• M. W.: 390.4618864
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 7-[(1R,2R,3R)-2-[4,4-difluoro-3-oxo(6,6,7,7,8,8,8-^2H₇)octyl]-3-hydroxy-5-oxocyclopentyl]heptanoic acid
• IUPAC Traditional name: 7-[(1R,2R,3R)-2-[4,4-difluoro-3-oxo(6,6,7,7,8,8,8-^2H₇)octyl]-3-hydroxy-5-oxocyclopentyl]heptanoic acid
• Synonyms: (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid-d7; Ru 0211-d7

PROPERTIES

• Apperance: Thick Yellow Oil
• Solubility: Chloroform
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms o

REFERENCES

• Farthing, M., et al.: Drugs, 56, 11 (1998)
• Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (1998)
• Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (1998)
• Coremans, G., et al.: Digestion, 67, 82 (1998)