Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether

• Catalog No.: L472240
• CAS Number: 79902-31-1
• M. F.: C25H42O4Si
• M. W.: 434.68408

SYNONYMS

• IUPAC name: (4R,6R)-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-[(tert-butyldimethylsilyl)oxy]oxan-2-one
• IUPAC Traditional name: (4R,6R)-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-[(tert-butyldimethylsilyl)oxy]oxan-2-one
• Synonyms: (4R,6R)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-2H-pyran-2-one

DATABASE IDS

• CAS Number: 79902-31-1

PROPERTIES

• Apperance: White Solid
• Solubility: Dichloromethane
• Solubility: DMF
• Solubility: DMSO
• Solubility: Ether
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

An intermediate used for synthesis of Simvastatin precursor (H941625).

REFERENCES

• Hoffman, W., et al.: J. Med. Chem., 29, 849 (1986)
• Jacobsen, W., et al.: Drug Metab. Dispos., 27, 173 (1986)
• Igel, M., et al.: Eur. J. Clin. Pharmacol., 57, 357 (1986)