Losartan-d4 Carboxylic Acid

• Catalog No.: L470513
• CAS Number: 1246820-62-1
• M. F.: C22H21ClN6O2
• M. W.: 436.89414
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl](^2H₄)phenyl}methyl)-1H-imidazole-5-carboxylic acid
• IUPAC Traditional name: 2-butyl-5-chloro-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl](^2H₄)phenyl}methyl)imidazole-4-carboxylic acid
• Synonyms: EXP 3174-d4; 2-Butyl-4-chloro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid-d4

DATABASE IDS

• CAS Number: 1246820-62-1

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 105-110°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A isotopically labelled metabolite of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist.

REFERENCES

• Pieter, B.M.W.M., et al.: Hypertension, Supp. III, 18, 5, (1991)
• Chang, L.L., et al.: J. Med. Chem., 36, 2558 (1993)