Losartan-d3 Carboxylic Acid

• Catalog No.: L470512
• CAS Number: 1189729-40-5
• M. F.: C22H21ClN6O2
• M. W.: 436.89414
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-[(4,4,4-^2H₃)butyl]-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylic acid
• IUPAC Traditional name: 2-[(4,4,4-^2H₃)butyl]-5-chloro-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)imidazole-4-carboxylic acid
• Synonyms: 2-(Butyl-d3)-4-chloro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid; EXP 3174-d3

DATABASE IDS

• CAS Number: 1189729-40-5

PROPERTIES

• Apperance: Off-White to Light-Brown Solid
• Melting Point: 125-127°C
• Solubility: Dimethyl Sulfoxide
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: Very Hygroscopic

DETAILS

Description (English)

A isotopically labelled metabolite of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist.

REFERENCES

• Pieter, B.M.W.M., et al.: Hypertension, Supp. III, 18, 5, (1991)
• Chang, L.L., et al.: J. Med. Chem., 36, 2558 (1993)