Losartan Carboxaldehyde-d3

• Catalog No.: L470507
• M. F.: C22H21ClN6O
• M. W.: 420.89474
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2-[(4,4,4-^2H₃)butyl]-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carbaldehyde
• IUPAC Traditional name: 2-[(4,4,4-^2H₃)butyl]-5-chloro-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)imidazole-4-carbaldehyde
• Synonyms: EXP 3179; DUP 167; 2-(Butyl-d3)-4-chloro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 82-84°C
• Solubility: Chloroform
• Solubility: DMF
• Solubility: DMSO
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A labelled intermediate in the synthesis of the EXP 3174, a metabolite of Losartan.

REFERENCES

• Pieter, B.M.W.M., et al.: Hypertension, Supp. III, 18, 5, (1991)
• Chang, L.L., et al.: J. Med. Chem., 36, 2558 (1993)