Losartan Carboxaldehyde

• Catalog No.: L470505
• CAS Number: 114798-36-6
• M. F.: C22H21ClN6O
• M. W.: 420.89474
• Storage: Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carbaldehyde
• IUPAC Traditional name: 2-butyl-5-chloro-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)imidazole-4-carbaldehyde
• Synonyms: 2-Butyl-4-chloro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde; DUP 167; EXP 3179

DATABASE IDS

• CAS Number: 114798-36-6

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 84-86°C
• Solubility: Chloroform
• Solubility: Dimethyl Formamide
• Solubility: Dimethyl Sulfoxide
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Losartan. An intermediate in the synthesis of the EXP 3174.

REFERENCES

• Pieter, B.M.W.M., et al.: Hypertension, Supp. III, 18, 5, (1991)
• Chang, L.L., et al.: J. Med. Chem., 36, 2558 (1993)