Losartan Potassium Salt

• Catalog No.: L470500
• CAS Number: 124750-99-8
• M. F.: C44H45Cl2KN12O2
• M. W.: 883.9116
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: potassium [2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl](^2H₄)phenyl}methyl)-1H-imidazol-5-yl]methanol [2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazol-5-yl]methanolate
• IUPAC Traditional name: potassium [2-butyl-5-chloro-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl](^2H₄)phenyl}methyl)imidazol-4-yl]methanol [2-butyl-5-chloro-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)imidazol-4-yl]methanolate
• Synonyms: DuP753; 2-Butyl-4-chloro-1-[[2’-(1H-tetrazol-5yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol Potassium Salt; MK-954; Cozaar

DATABASE IDS

• CAS Number: 124750-99-8

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 263-265°C
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

REFERENCES

• Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990)
• McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1990)
• Pitt, B., et al.: Lancet, 355, 1582 (2000)