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Lofepramine

Catalog No. L469380 Name Toronto Research Chemicals
CAS Number 23047-25-8 Website http://www.trc-canada.com
M. F. C26H27ClN2O Telephone +1 (416) 665-9696
M. W. 418.95838 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 128105

SYNONYMS

IUPAC name
2-[(3-{2-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)(methyl)amino]-1-(4-chlorophenyl)ethan-1-one
IUPAC Traditional name
lofepramine
Synonyms
Lopramine
Leo 640
1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]ethanone
Amplit
4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl-methylamino]acetophenone

DATABASE IDS

CAS Number 23047-25-8

PROPERTIES

Certificate of Analysis Download
Apperance Light Yellow Solid
Melting Point 103-105°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Psychotropic drug related to imipramine. Antidepressant.

REFERENCES

  • Tulic, J.R., et al.: Acta Pharmacol. Toxicol., 32, 304 (1973)
  • Plym Forshell, G., et al.: Xenobiotica, 5, 73 (1973)
  • Wright, S., et al.: Arzneim.-Forsch., 26, 1167 (1973)