Lithocholylglycine-d5

• Catalog No.: L469202
• M. F.: C26H43NO4
• M. W.: 433.62392

SYNONYMS

• IUPAC name: 2-[(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R)-5-hydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]acetic acid
• IUPAC Traditional name: [(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R)-5-hydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]acetic acid
• Synonyms: N-(3α-Hydroxy-5β-cholanoyl)glycine-d5; 3α-Hydroxy-5β-cholanoylglycine-d5; 3α-Hydroxy-5β-cholanic Αcid-d5 Glycine Ester; N-[(3α,5β)-3-Ηydroxy-24-oxocholan-24-yl]glycine-d5

DETAILS

Description (English)

A labelled metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.

REFERENCES

• Ishikawa, H., et al.: J. Lipid. Res., 40, 1920 (1999)
• Gustafsson, U., et al.: Eur. J. Clin. Invest., 30, 1099 (1999)
• Gowda, G., et al.: Lipids, 41, 591 (1999)
• Lindon, J., et al.: Pharm. Res., 23, 1075 (1999)