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Lithocholylglycine

Catalog No. L469200 Name Toronto Research Chemicals
CAS Number 474-74-8 Website http://www.trc-canada.com
M. F. C26H43NO4 Telephone +1 (416) 665-9696
M. W. 433.62392 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 172356

SYNONYMS

IUPAC name
2-[(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]pentanamido]acetic acid
IUPAC Traditional name
glycolithocholic acid
Synonyms
N-(3α-Hydroxy-5β-cholanoyl)glycine
3α-Hydroxy-5β-cholanoylglycine
3α-Hydroxy-5β-cholanic Αcid Glycine Ester
N-[(3α,5β)-3-Ηydroxy-24-oxocholan-24-yl]glycine

DATABASE IDS

CAS Number 474-74-8

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 176-178°C
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.

REFERENCES

  • Ishikawa, H., et al.: J. Lipid. Res., 40, 1920 (1999)
  • Gustafsson, U., et al.: Eur. J. Clin. Invest., 30, 1099 (1999)
  • Gowda, G., et al.: Lipids, 41, 591 (1999)
  • Lindon, J., et al.: Pharm. Res., 23, 1075 (1999)