Lithocholic acid

• Catalog No.: L469180
• CAS Number: 434-13-9
• M. F.: C24H40O3
• M. W.: 376.5726
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanoic acid
• IUPAC Traditional name: lithocholic acid
• Synonyms: 3-Hydroxycholan-24-oic Acid; NSC 683770; (3α,5β)-3-Hydroxycholan-24-oic Acid; 3α-Hydroxycholanic Acid; 3α-Hydroxy-5β-cholan-24-oate; 17β-(1-Methyl-3-carboxypropyl)etiocholan-3α-ol; 3α-Hydroxy-5β-cholanoic Acid; 3α-Hydroxy-5β-cholan-24-oic acid; 3α-Hydroxy-5β-cholanic acid

DATABASE IDS

• CAS Number: 434-13-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 189-191°C
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.

REFERENCES

• Brindle, J., et al.: Nat. Med., 12, 1439 (2002)
• Lindon, J., et al.: Biomarkers, 9, 1 (2002)
• Holmes, E., et al.: Cell, 134, 714 (2002)