Lisuride

• Catalog No.: L469075
• CAS Number: 18016-80-3
• M. F.: C20H26N4O
• M. W.: 338.44664

SYNONYMS

• IUPAC name: 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),2,9,12,14-pentaen-4-yl]urea
• IUPAC Traditional name: lisuride
• Synonyms: 1,1-Diethyl-3-((6aR,9S)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl)urea; 9-(3,3-Diethylureido)-4,6,6a,7,8,9-hexahydro-7-methylindolo[4,3-fg]quinoline; 1,1-Diethyl-3-(D-6-methylisoergolen-8-yl)urea; Mesorgydine; Lysuride; N'-[(8α)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylurea; (+)-(5R,8S)-Lisuride; 3-(9,10-Didehydro-6-methylergolin-8α-yl)-1,1-diethylurea; N-(D-6-Methyl-8-isoergolenyl)-N',N'-diethylurea; Lisurid; Methylergol Carbamide

DATABASE IDS

• CAS Number: 18016-80-3

DETAILS

Description (English)

A dopamine and serotonin receptor partial agonist with high affinity for the dopamine D2, D3 and D4 receptors, as well as serotonin 5-HT1A and 5-HT2A/C receptors. An anti-parkinson agent.

REFERENCES

• De Keyser, J. et al.: Prog. Neuro-Psychopharmacol. Biol. Psych., 19, 1147 (1995)
• Bakker, R.A. et al.: Mol. Pharmacol., 65, 1048 (1995)
• Woitalla, D. et al.: J. Neural Trans. Supp., 68, 89 (1995)