(+/-)-Lisofylline-d6_Molecular_structure_CAS_)

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(+/-)-Lisofylline-d6
Catalog No.	L469053	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C13H20N4O3	Telephone	+1 (416) 665-9696
M. W.	280.3229	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 172355

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SYNONYMS

IUPAC name

1-[5-hydroxy(4,4,5,6,6,6-²H₆)hexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

IUPAC Traditional name

1-[5-hydroxy(4,4,5,6,6,6-²H₆)hexyl]-3,7-dimethylpurine-2,6-dione

Synonyms

Pentoxifylline-d6 Alcohol

3,7-Dihydro-1-(5-hydroxyhexyl-d6)-3,7-dimethyl-1H-purine-2,6-dione

(+/-)-1-(5-Hydroxyhexyl-d6)-3,7-dimethylxanthine

1-(5-Hydroxyhexyl-d6)theobromine

BL 194-d6

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)

A major oxidative labelled metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.

REFERENCES

Clarke, E., et al.: Cancer Res., et al.: 56, 105 (1996)
Itani, S., et al.: Metabolism, 50, 553 (1996)
Itani, S., et al.: Diabetes, 51, 2005(1996)
Yu, C., et al.: J. Biol. Chem., 277, 50230 (1996)