(+/-)-Lisofylline-d6

• Catalog No.: L469052
• CAS Number: 1185995-26-9
• M. F.: C13H20N4O3
• M. W.: 280.3229
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 1-(5-hydroxyhexyl)-3,7-bis(^2H₃)methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• IUPAC Traditional name: 1-(5-hydroxyhexyl)-3,7-bis(^2H₃)methylpurine-2,6-dione
• Synonyms: Pentoxifylline-d6 Alcohol; 1-(5-Hydroxyhexyl)theobromine-d6; BL 194-d6; 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-(dimethyl-d6)-1H-purine-2,6-dione; (+/-)-1-(5-Hydroxyhexyl)-3,7-(dimethyl-d6)xanthine; Hydroxypentoxifylline-d6

DATABASE IDS

• CAS Number: 1185995-26-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 126-128°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A major oxidative labelled metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.

REFERENCES

• Clarke, E., et al.: Cancer Res., et al.: 56, 105 (1996)
• Itani, S., et al.: Metabolism, 50, 553 (1996)
• Itani, S., et al.: Diabetes, 51, 2005(1996)
• Yu, C., et al.: J. Biol. Chem., 277, 50230 (1996)