Lincomycin-d3

• Catalog No.: L466202
• M. F.: C18H34N2O6S
• M. W.: 406.53736
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-(^2H₃)methyl-4-propylpyrrolidine-2-carboxamide
• IUPAC Traditional name: (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-(^2H₃)methyl-4-propylpyrrolidine-2-carboxamide
• Synonyms: Lincogap-d3; NSC 70731-d3; Lincocin-d3; (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-d3-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-threo-α-D-galacto-octopyranoside; U 10149a-d3

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 63-66°C
• Solubility: Chloroform
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled Lincomycin. An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.

REFERENCES

• Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962)
• Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1962)
• Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1962)