Lincomycin Hydrochloride

• Catalog No.: L466200
• CAS Number: 859-18-7
• M. F.: C18H35ClN2O6S
• M. W.: 442.9983
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2R)-N-{2-hydroxy-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
• IUPAC Traditional name: (2R)-N-{2-hydroxy-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
• Synonyms: Lincogap; NSC 70731; (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D3-threo-α-D-galactooctopyranoside Hydrochloride; Lincocin; U 10149a

DATABASE IDS

• CAS Number: 859-18-7

PROPERTIES

• Apperance: White Crystalline Solid
• Melting Point: 148-150°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.

REFERENCES

• Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962)
• Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1962)
• Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1962)