Limaprost

• Catalog No.: L461500
• CAS Number: 74397-12-9
• M. F.: C22H36O5
• M. W.: 380.51824

SYNONYMS

• IUPAC name: (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methylnon-1-en-1-yl]-5-oxocyclopentyl]hept-2-enoic acid
• IUPAC Traditional name: limaprost
• Synonyms: 17S,20-Dimethyl-trans-Δ2-PGE1; (2E,11α,13E,15S,17S)-11,15-Dihydroxy-17,20-dimethyl-9-oxo-prosta-2,13-dien-1-oic Acid; (2E)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-2-heptenoic Acid; ONO 1206; OP 1206

DATABASE IDS

• CAS Number: 74397-12-9

DETAILS

Description (English)

Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.

REFERENCES

• Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980)
• Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1980)
• Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1980)
• Ishizaki, T., et al.: Chest, 85, 382 (1980)