LG 100268

• Catalog No.: L397650
• CAS Number: 153559-76-3
• M. F.: C24H29NO2
• M. W.: 363.49256
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid
• IUPAC Traditional name: 6-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid
• Synonyms: LGD 100268; LGD 1268; ALRT 268; CD 3127; 6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-Pyridinecarboxylic Acid; AGN 192620; LG 268

DATABASE IDS

• CAS Number: 153559-76-3

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 275-277°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).

REFERENCES

• Clyne, C., et al.: J. Biol. Chem., 277, 20591 (2002)
• Santen, R., et al.: J. Clin. Endocrinol. Metab., 87, 3007 (2002)
• Falender, A., et al.: Endocrinology, 144, 3598 (2002)
• Sablin, E., et al.: Mol. Cell., 11, 1575 (2003)