Lewis X Trisaccharide, 4-Methylumbelliferyl Glycoside

• Catalog No.: L395600
• CAS Number: 359436-57-0
• M. F.: C30H41NO17
• M. W.: 687.64304
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl]acetamide
• IUPAC Traditional name: N-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-2-[(4-methyl-2-oxochromen-7-yl)oxy]-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl]acetamide
• Synonyms: Gal1-b-4[Fuc1-α-3]GlcNAc-4-MU; 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3-O-(α-L-fucopyranosyl)-4-O-(β-D-galactopyranosyl)-β-D-glucopyranoside

DATABASE IDS

• CAS Number: 359436-57-0

PROPERTIES

• Apperance: Off-White to Grey Solid
• Melting Point: >170°C (dec.)
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer
• Storage Warning: Hygroscopic

DETAILS

Description (English)

Lewis x and related compounds are ligands for P- and E-selectins. Lewis x is a developmentally regulated antigen and has been suggested to be a tumor marker. These compounds may also act as anti-inflammatory agents.

REFERENCES

• Lasky, L.A.: Science, 258, 964 (1992)
• Mulligan, M.S., et al.: Nature, 364, 149 (1992)
• Mulligan, M.S., et al.: J. Exp. Med., 178, 623 (1992)
• Travis, J.: Science, 260, 906 (1993)