Leuprolide-d5 Acetate

• Catalog No.: L330602
• M. F.: C61H88N16O14
• M. W.: 1269.45022
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-1-{5-carbamimidamido-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl}-N-(^2H₅)ethylpyrrolidine-2-carboxamide; acetic acid
• IUPAC Traditional name: (2S)-1-{5-carbamimidamido-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(3H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl}-N-(^2H₅)ethylpyrrolidine-2-carboxamide; acetic acid
• Synonyms: TAP 144SR-d5 Acetate; Leuprorelin-d5 Acetate; Abbott 43818-d5 Acetate; 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamideluteinizing-d5 Acetate; A 43818-d5 Acetate; Hormone-Releasing Factor (Pig) Acetate; Lupron-d5 Acetate; Procren Depot-d5 Acetate; Procrin-d5 Acetate; Prostap-d5 Acetate; TAP 144-d5 Acetate

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >166°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).

REFERENCES

• Vilchez-Martinez, J.A., et al.: Biochem. Biophys. Res. Commun., 59, 1226 (1974)
• Sennello, L.T., et al.: J. Pharm. Sci., et al.: 75, 158 (1974)
• Wheeler, J.M., et al.: Am.J. Obstet. Gynecol., 167, 1367 (1974)
• Eri, L.M., et al.: J. Urol., 150, 359 (1974)