Leuprolide Acetate

• Catalog No.: L330600
• CAS Number: 74381-53-6
• M. F.: C61H88N16O14
• M. W.: 1269.45022
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-1-{5-carbamimidamido-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl}-N-ethylpyrrolidine-2-carboxamide; acetic acid
• IUPAC Traditional name: (2S)-1-{5-carbamimidamido-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(3H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl}-N-ethylpyrrolidine-2-carboxamide; acetic acid
• Synonyms: Procren Depot; A 43818; Prostap; 6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamideluteinizing Hormone-Releasing Factor Acetate(Pig); Abbott 43818; Leuprorelin Acetate; Lupron; Procrin; TAP 144; TAP 144SR

DATABASE IDS

• CAS Number: 74381-53-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 150-155°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).

REFERENCES

• Vilchez-Martinez, J.A., et al.: Biochem. Biophys. Res. Commun., 59, 1226 (1974)
• Sennello, L.T., et al.: J. Pharm. Sci., et al.: 75, 158 (1974)
• Wheeler, J.M., et al.: Am.J. Obstet. Gynecol., 167, 1367 (1974)
• Eri, L.M., et al.: J. Urol., 150, 359 (1974)