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Leuprolide Acetate

Catalog No. L330600 Name Toronto Research Chemicals
CAS Number 74381-53-6 Website http://www.trc-canada.com
M. F. C61H88N16O14 Telephone +1 (416) 665-9696
M. W. 1269.45022 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer, Under Inert Atmosphere Chembase ID: 172270

SYNONYMS

IUPAC name
(2S)-1-{5-carbamimidamido-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl}-N-ethylpyrrolidine-2-carboxamide; acetic acid
IUPAC Traditional name
(2S)-1-{5-carbamimidamido-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(3H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl}-N-ethylpyrrolidine-2-carboxamide; acetic acid
Synonyms
Procren Depot
A 43818
Prostap
6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamideluteinizing Hormone-Releasing Factor Acetate(Pig)
Abbott 43818
Leuprorelin Acetate
Lupron
Procrin
TAP 144
TAP 144SR

DATABASE IDS

CAS Number 74381-53-6

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 150-155°C (dec.)
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
Synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).

REFERENCES

  • Vilchez-Martinez, J.A., et al.: Biochem. Biophys. Res. Commun., 59, 1226 (1974)
  • Sennello, L.T., et al.: J. Pharm. Sci., et al.: 75, 158 (1974)
  • Wheeler, J.M., et al.: Am.J. Obstet. Gynecol., 167, 1367 (1974)
  • Eri, L.M., et al.: J. Urol., 150, 359 (1974)