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trans-Latanoprost

Catalog No. L177300 Name Toronto Research Chemicals
CAS Number 913258-34-1 Website http://www.trc-canada.com
M. F. C26H40O5 Telephone +1 (416) 665-9696
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Purity Email info@trc-canada.com
Storage -80°C Freezer Chembase ID: 536

SYNONYMS

IUPAC name
propan-2-yl (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
IUPAC Traditional name
latanaprost
Synonyms
5,6-trans-Latanoprost
(5E)-Latanoprost
(5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester

DATABASE IDS

CAS Number 913258-34-1

PROPERTIES

Certificate of Analysis Download
Apperance Colourless Oil
Solubility Chloroform
MSDS Link Download
Storage Condition -80°C Freezer

DETAILS

Description (English)
Prostaglandin analog; prodrug of active acid metabolite. It is a synthetic derivative of the natural prostaglandin PGF2α, used as an anti-glaucoma agent that is effective in various types of glaucoma and ocular hypertension.

REFERENCES

  • Resul, B., et al.: J. Med. Chem., 36, 2242 (1993)
  • Toris, C., et al.: Ophthalmology, 100, 1297 (1993)
  • Holmstrom, S., et al.: Curr. Med. Res. Op., 21, 1875 (1993)