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Lasofoxifene 2-Oxide_Molecular_structure_CAS_366017-88-1)
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Lasofoxifene 2-Oxide

Catalog No. L176515 Name Toronto Research Chemicals
CAS Number 366017-88-1 Website http://www.trc-canada.com
M. F. C28H29NO3 Telephone +1 (416) 665-9696
M. W. 427.53476 Fax +1 (416) 665-4439
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Storage Chembase ID: 172231

SYNONYMS

IUPAC name
1-(2-{4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy}ethyl)pyrrolidin-2-one
IUPAC Traditional name
1-(2-{4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy}ethyl)pyrrolidin-2-one
Synonyms
1-[2-[4-[(1R,2S)-1,2,3,4-Tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenoxy]ethyl]-2-pyrrolidinone

DATABASE IDS

CAS Number 366017-88-1

PROPERTIES

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MSDS Link Download

DETAILS

Description (English)
A metabolite of Lasofoxifene (L176500) in humans, (oxidation on the pyrrolidine moiety).

REFERENCES

  • Monks, T., et al.: Toxicol. Appl. Pharmacol., 112, 2 (1992)
  • Luisetto, G., et al.: Bone Miner., 22, 9 (1992)
  • Rosati, R., et al.: J. Med. Chem., 41, 2928 (1992)
  • Mattiuz, E., et al.: Drug Metab. Dispos., 31, 88 (1992)
  • Kamel, A., et al.: Curr Drug. Metab.