Lasofoxifene 2-Oxide

• Catalog No.: L176515
• CAS Number: 366017-88-1
• M. F.: C28H29NO3
• M. W.: 427.53476

SYNONYMS

• IUPAC name: 1-(2-{4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy}ethyl)pyrrolidin-2-one
• IUPAC Traditional name: 1-(2-{4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy}ethyl)pyrrolidin-2-one
• Synonyms: 1-[2-[4-[(1R,2S)-1,2,3,4-Tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenoxy]ethyl]-2-pyrrolidinone

DATABASE IDS

• CAS Number: 366017-88-1

DETAILS

Description (English)

A metabolite of Lasofoxifene (L176500) in humans, (oxidation on the pyrrolidine moiety).

REFERENCES

• Monks, T., et al.: Toxicol. Appl. Pharmacol., 112, 2 (1992)
• Luisetto, G., et al.: Bone Miner., 22, 9 (1992)
• Rosati, R., et al.: J. Med. Chem., 41, 2928 (1992)
• Mattiuz, E., et al.: Drug Metab. Dispos., 31, 88 (1992)
• Kamel, A., et al.: Curr Drug. Metab.