rac Lasofoxifene-d4

• Catalog No.: L176502
• M. F.: C28H31NO2
• M. W.: 413.55124

SYNONYMS

• IUPAC name: (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)(^2H₄)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
• IUPAC Traditional name: (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)(^2H₄)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
• Synonyms: rel-(5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy-d4]phenyl]-2-naphthalenol; rac-(5R-cis)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy-d4]phenyl]-2-naphthalenol

DETAILS

Description (English)

rac Labelled Lasofoxifene (L176500). A next-generation selective estrogen receptor modulator for treating disorders associated with increased bone turnover and osteopenia.

REFERENCES

• Baumann, R., et al.: Biochem. Pharmacol., 55, 841 (1998)
• Ammann, P., et al.: Osteoporos Int., 10, 369 (1998)
• Alexandersen, P., et al.: J. Clin. Endocrinol. Metab., 86, 755 (1998)
• Bourrin, S., et al.: Bone, 30, 195 (1998)
• Buzdar, A., et al.: J. Clin. O