Loxapine-d8 Hydrochloride

• Catalog No.: L472752
• CAS Number: 1246820-19-8
• M. F.: C18H19Cl2N3O
• M. W.: 364.26896
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 13-chloro-10-[4-methyl(^2H₈)piperazin-1-yl]-2-oxa-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene hydrochloride
• IUPAC Traditional name: 13-chloro-10-[4-methyl(^2H₈)piperazin-1-yl]-2-oxa-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene hydrochloride
• Synonyms: Oxilapine-d8 Hydrochloride; SUM-3170-d8 Hydrochloride; CL-62362-d8 Hydrochloride; S-805-d8 Hydrochloride; 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine-d8 Hydrochloride

DATABASE IDS

• CAS Number: 1246820-19-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 160-164°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent.

REFERENCES

• Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993)
• Fiorella, D., et al.: Psychopharmacology, 121, 347 (1993)
• Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)