Leukotriene E4-d11

• Catalog No.: L330352
• M. F.: C23H37NO5S
• M. W.: 439.60858

SYNONYMS

• IUPAC name: (5S,6R,7E,9E,11Z,14Z)-6-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-5-hydroxy(16,16,17,17,18,18,19,19,20,20,20-^2H₁₁)icosa-7,9,11,14-tetraenoic acid
• IUPAC Traditional name: (5S,6R,7E,9E,11Z,14Z)-6-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-5-hydroxy(16,16,17,17,18,18,19,19,20,20,20-^2H₁₁)icosa-7,9,11,14-tetraenoic acid
• Synonyms: (5S,6R,7E,9E,11Z,14Z)-6-[[(2R)-2-Amino-2-carboxyethyl]thio]-5-hydroxy-7,9,11,14-eicosatetraenoic Acid-d11; LTE4-d11; Leukotriene E-d11

DETAILS

Description (English)

A labelled metabolite of Arachidonic acid (A765000) via the lipoxygenase pathway, chemically related to the prostaglandins and thromboxanes. The name leukotrienes was applied because of their origin in leukocytes and their conjugated triene structures.

REFERENCES

• Borgeat, P., et al.: J. Med. Chem., 24, 121 (1981)
• Kan, K., et al.: Eur. J. Pharmacol., 544, 153 (1981)
• Sam, T., et al.: J. Pharmacol. Sci., 103, 189 (1981)
• Darmani, N., et al.: Brain Res., 1248, 40 (1981)