ent-Lamivudine

• Catalog No.: L172505
• CAS Number: 134680-32-3
• M. F.: C8H11N3O3S
• M. W.: 229.25624
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
• IUPAC Traditional name: 2'3' dideoxy 3' thiacytidine
• Synonyms: 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; cis(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane; (2S-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; 2',3'-Dideoxy-3'-thiacytidine; (+)-BCH 189; 2'-Deoxy-3'-thiacytidine; 3TC; NSC 620753

DATABASE IDS

• CAS Number: 134680-32-3

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 164-166°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

An enantiomer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.

REFERENCES

• Pepe, G. et al.: Eur. J. Med. Chem., 31, 775 (1996)
• Marr, E. et al.: Antiviral Res., 28, 1 (1996)
• Parikh, U.M. et al.: Antimicrob. Agents Chemother., 49, 1139 (1996)