Lamivudine-15N2,13C

• Catalog No.: L172502
• M. F.: C8H11N3O3S
• M. W.: 232.23571263
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydro(2-^1^3C,1,3-^1^5N₂)pyrimidin-2-one
• IUPAC Traditional name: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl](2-^1^3C,1,3-^1^5N₂)pyrimidin-2-one
• Synonyms: Lamivir-15N2,13C; 3TC-15N2,13C; Hepitec-15N2,13C; Epivir HBV-15N2,13C; (-)-2'-Deoxy-3'-thiacytidine-15N2,13C; 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone-15N2,13C; (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone-15N2,13C; (-)-BCH 189-15N2,13C; Heptodin-15N2,13C; Heptovir-15N2,13C; L-SddC-15N2,13C; Virolam-15N2,13C; Zeffix-15N2,13C; β-L-2',3'-Dideoxy-3'-thiacytidine-15N2,13C; β-L-3'-Thia-2',3'-dideoxycytidine-15N2,13C

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 125-130°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled Lamivudine. A reverse transcriptase inhibitor. Antiviral.

REFERENCES

• Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944)
• Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1944)
• Perry, C.M., et al.: Drugs, 53, 657 (1944)