Lamivudine

• Catalog No.: L172500
• CAS Number: 134678-17-4
• M. F.: C8H11N3O3S
• M. W.: 229.25624
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
• IUPAC Traditional name: lamivudine
• Synonyms: 3TC; 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; β-L-2',3'-Dideoxy-3'-thiacytidine; (-)-2'-Deoxy-3'-thiacytidine; Zeffix; (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (-)-BCH 189; Epivir HBV; Hepitec; Heptodin; L-SddC; Lamivir; Virolam; β-L-3'-Thia-2',3'-dideoxycytidine; Heptovir

DATABASE IDS

• CAS Number: 134678-17-4

PROPERTIES

• Apperance: White Solid
• Melting Point: 171-173°C
• Solubility: Sparingly Sol. in Ethanol
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.

REFERENCES

• Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944)
• Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1944)
• Perry, C.M., et al.: Drugs, 53, 657 (1944)