L-659989

• Catalog No.: L009500
• CAS Number: 113787-28-3
• M. F.: C24H32O8S
• M. W.: 480.57108

SYNONYMS

• IUPAC name: (2S,5S)-2-(3-methanesulfonyl-5-methoxy-4-propoxyphenyl)-5-(3,4,5-trimethoxyphenyl)oxolane
• IUPAC Traditional name: (2S,5S)-2-(3-methanesulfonyl-5-methoxy-4-propoxyphenyl)-5-(3,4,5-trimethoxyphenyl)oxolane
• Synonyms: (2R,5R)-rel-Tetrahydro-2-[3-methoxy-5-(methylsulfonyl)-4-propoxyphenyl]-5-(3,4,5-trimethoxyphenyl)furan; trans-(±)-Tetrahydro-2-[3-methoxy-5-(methylsulfonyl)-4-propoxyphenyl]-5-(3,4,5-trimethoxyphenyl)furan; L 659989

DATABASE IDS

• CAS Number: 113787-28-3

DETAILS

Description (English)

L-659989 is a platelet-activating factor (PAF) receptor antagonist. L-659989 is also a potent inhibitor of phospholipase D activity at higher concentrations. L-659989 showed cardioprotective effects as it inhibited heart injury from ischemia and reperfusi

REFERENCES

• Hussaini, I.M. et al.: Acta Pharmacol. Sin., 21, 897 (2000)
• Gomez-M. et al.: Biochim. Biophys. Acta, 1438, 247 (2000)
• Ioculano, M. et al.: J. Cardio. Pharmacol., 23, 7 (2000)