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KRN7000

Catalog No. K660000 Name Toronto Research Chemicals
CAS Number 158021-47-7 Website http://www.trc-canada.com
M. F. C50H99NO9 Telephone +1 (416) 665-9696
M. W. 858.32236 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 154862

SYNONYMS

IUPAC name
N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadecan-2-yl]hexacosanamide
IUPAC Traditional name
α-GalCer
Synonyms
N-[(1S,2S,3R)-1-[(α-D-Galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]hexacosanamide

DATABASE IDS

CAS Number 158021-47-7

PROPERTIES

Certificate of Analysis Download
Apperance White to Off-White Solid
Melting Point 125-130°C
Solubility Pyridine
Solubility 0.2mg per ml PBS plus 0.5% Tween-20 and sonicate for 2hrs
MSDS Link Download
Storage Condition -20°C Freezer
Storage Warning Hygroscopic

DETAILS

Description (English)
Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity

REFERENCES

  • Morita, M., et al.: J. Med. Chem., 38, 2176 (1995)
  • Sakai, T., et al.: J. Med. Chem., 42, 1836 (1995)