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(S)-Ketorolac

Catalog No. K235605 Name Toronto Research Chemicals
CAS Number 66635-92-5 Website http://www.trc-canada.com
M. F. C15H13NO3 Telephone +1 (416) 665-9696
M. W. 255.26862 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 172112

SYNONYMS

IUPAC name
(1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
IUPAC Traditional name
(1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Synonyms
(1S)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid
(-)-Ketorolac
S-(-)-Ketorolac

DATABASE IDS

CAS Number 66635-92-5

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 160-167°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
(S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.

REFERENCES

  • Rooks, W.H., et al.: Agents Actions, 12, 684 (1982)
  • Guzman, A., et al.: J. Med. Chem., 29, 589 (1982)
  • McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1982)