all-trans 4-Keto Retinoic Acid-(9-methyl)-d3

• Catalog No.: K204983
• M. F.: C20H26O3
• M. W.: 314.41864
• Storage: Amber Vial, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: (2E,4E,6E,8E)-7-(^2H₃)methyl-3-methyl-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC Traditional name: (2E,4E,6E,8E)-7-(^2H₃)methyl-3-methyl-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• Synonyms: 4-Oxo-all-trans-retinoic Acid-7-d3; 4-Ketoretinoic Acid-7-d3; 4-Oxotretinoin-d3; Ro 11-4824-7-d3; 4-Oxoretinoic Acid-7-d3; 4-Oxo-atRA-7-d3; 4-keto-Retinoic Acid-7-d3; Ro 12-4824-7-d3; all-trans-4-Oxoretinoic Acid-7-d3

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 178-180°C
• Solubility: Chloroform
• Storage Condition: Amber Vial, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

A deuterated metabolite of all-trans-Retinoic Acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).

REFERENCES

• Andreola, F., et al.: J. Biol. Chem., 279, 3434 (2004)
• Armstrong, J., et al.: Biochem. Pharmacol., 69, 1299 (2004)
• Njar, V., et al.: Bioorg. Med. Chem., 14, 4323 (2004)
• Veal, G., et al.: Br. J. Cancer, 96, 424 (2004)