Keto Itraconazole

• Catalog No.: K195000
• CAS Number: 112560-33-5
• M. F.: C35H36Cl2N8O5
• M. W.: 719.61694
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-1-(3-oxobutan-2-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC Traditional name: 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2-(3-oxobutan-2-yl)-1,2,4-triazol-3-one
• Synonyms: rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methyl-2-oxopropyl)-3H-1,2,4-triazol-3-one; keto-ITZ

DATABASE IDS

• CAS Number: 112560-33-5

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 151-154°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A new metabolite of Itraconazole.

REFERENCES

• Back, D., et al.: Br. J. Clin. Pharmacol., 32, 624 (1991)
• Barone, J., et al.: Antimicrob. Agents Chemother., 37, 778 (1991)
• Haria, M., et al.: Drugs, 51, 585 (1991)
• Kivisto, K., et al.: Pharmacol. Toxicol., 84, 94 (1991)
• Lin, Y., et al.: Mol. Pharmacol