(-)-Keto Cyclazocine

• Catalog No.: K187500
• CAS Number: 36292-69-0
• M. F.: C18H23NO2
• M. W.: 285.38072

SYNONYMS

• IUPAC name: (1S,13R)-10-(cyclopropylmethyl)-4-hydroxy-1,13-dimethyl-10-azatricyclo[7.3.1.0^2,^7]trideca-2(7),3,5-trien-8-one
• IUPAC Traditional name: (1S,13R)-10-(cyclopropylmethyl)-4-hydroxy-1,13-dimethyl-10-azatricyclo[7.3.1.0^2,^7]trideca-2(7),3,5-trien-8-one
• Synonyms: Ketazocine; l-Ketocyclazocine; (2S,6R,11R)-3-(Cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-2,6-methano-3-benzazocin-1(2H)-one; NIH 8847; Win 34276; Ketocyclazocine; MCV 4513; NIH 10451

DATABASE IDS

• CAS Number: 36292-69-0

DETAILS

Description (English)

A kappa receptor agonist for the treatment of Crohn's disease and the symptoms associated with Crohn's disease.

REFERENCES

• Cheng, Y., et al.: Biochem. Pharmacol., 22, 3099 (1973)
• Wentland, M., et al.: Bioorg. Med. Chem. Lett., 11, 623 (1973)
• Zhang, A., et al.: J. Med. Chem., 47, 165 (1973)