11-Keto β-Boswellic Acid

• Catalog No.: K175200
• CAS Number: 17019-92-0
• M. F.: C30H46O4
• M. W.: 470.68384

SYNONYMS

• IUPAC name: (3R,4R,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
• IUPAC Traditional name: (3R,4R,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid
• Synonyms: 3α-Hydroxy-11-oxours-12-en-24-oic Acid; (3α,4β)-3-Hydroxy-11-oxours-12-en-23-oic Acid; 11-keto-β-Boswellic Acid; 11-Oxo-β-boswellic Acid

DATABASE IDS

• CAS Number: 17019-92-0

DETAILS

Description (English)

A constitutent of frankincense (olibanum) with anti-inflammatory properties. It has been shown to trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.

REFERENCES

• Liu, J. et al.: Carcinogen., 23, 2087 (2002)
• Sharma, S. et al.: Phytomed., 11, 255 (2002)
• Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2002)