Jervine

• Catalog No.: J211000
• CAS Number: 469-59-0
• M. F.: C27H39NO3
• M. W.: 425.60346
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (3S,3'R,7'aR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3'H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-11-one
• IUPAC Traditional name: (3S,3'R,7'aR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a-hexadecahydro-3'H-spiro[cyclohexa[a]fluorene-9,2'-furo[3,2-b]pyridine]-11-one
• Synonyms: (3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one

DATABASE IDS

• CAS Number: 469-59-0

PROPERTIES

• Apperance: Off-White to Tan Solid
• Melting Point: 242- 244°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Storage Condition: -20°C Freezer
• Storage Warning: Store in Freezer at - 20°C

DETAILS

Description (English)

Has antibacterial properties. Jervine demonstrates teratogenic properties. It is the starting material for C-nor-D-homosteroids. Jervine induces holoprosencephaly and blocks endogenous Sonic hedgehog signaling.

REFERENCES

• Cooper, M.K., et al.: Science, 280, 1603 (1998)