Ivermectin

• Catalog No.: I940800
• CAS Number: 70288-86-7
• M. F.: C48H74O14
• M. W.: 875.09276
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-6-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-{[(2R,4R,5S,6S)-5-{[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^4,^8.0^2^0,^2^4]pentacosane]-10',14',16',22'-tetraen-2'-one
• IUPAC Traditional name: (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-6-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-{[(2R,4R,5S,6S)-5-{[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^4,^8.0^2^0,^2^4]pentacosane]-10',14',16',22'-tetraen-2'-one
• Synonyms: Vermic; Ivosint; Mectizan; Heartgard 30; 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Ivomec; Stromectol; Uvemec; Zimecterin

DATABASE IDS

• CAS Number: 70288-86-7

PROPERTIES

• Apperance: White Solid
• Melting Point: 198-205°C
• Solubility: Chloroform
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca).

REFERENCES

• Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980)
• Campbell, W.C., et al.: Science, 221, 823 (1980)
• Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1980)
• Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1980)