Ivabradine-d3 Hydrochloride

• Catalog No.: I940502
• CAS Number: 1217809-61-4
• M. F.: C27H37ClN2O5
• M. W.: 505.04608
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl]methyl}(^2H₃)methylamino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one hydrochloride
• IUPAC Traditional name: 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl]methyl}(^2H₃)methylamino)propyl]-7,8-dimethoxy-4,5-dihydro-1H-3-benzazepin-2-one hydrochloride
• Synonyms: S-16257-d3; Procoralan-d3; Corlentor-d3; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino-d3]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride

DATABASE IDS

• CAS Number: 1217809-61-4

PROPERTIES

• Apperance: Tan Solid
• Melting Point: 99-102°C
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

Labelled Ivabradine (I940500). Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.

REFERENCES

• Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994)
• Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1994)
• Borer, J.S., et al.: Circulation, 107, 817 (1994)
• DiFrancesco, D., et al.: Drugs, 64, 1757 (1994)