Itraconazole

• Catalog No.: I937500
• CAS Number: 84625-61-6
• M. F.: C35H38Cl2N8O4
• M. W.: 705.63342
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
• IUPAC Traditional name: itraconazole
• Synonyms: Sporamelt; Sporanox; Triasporin; (+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one; Itrizole; Oriconazole; R-51211

DATABASE IDS

• CAS Number: 84625-61-6

PROPERTIES

• Apperance: White and Off-White Solid
• Melting Point: 164-166°C
• Solubility: Chloroform
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An orally active antimycotic structurally related to Ketoconazole. Antifungal.

REFERENCES

• Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984)
• Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1984)
• Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1984)